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Vitamin B12

Signs of vitamin B12 deficiency, and when to get tested

Tiredness, tingling and brain fog can all point to low B12. Here's what the symptoms are, who's most at risk, and how a simple test and treatment work.

  • Vitamin B12
  • 21 September 2026
  • 1 min read

In short

Vitamin B12 deficiency can cause tiredness, breathlessness, pins and needles, a sore tongue and problems with memory or concentration. It is more common in older adults, people following a vegan or vegetarian diet, and those with absorption problems. A blood test confirms it, and treatment is usually B12 injections or high-dose tablets. South London Clinic can test and treat at the same visit.

What B12 does

Vitamin B12 helps your body make red blood cells and keep the nervous system working. Because the body stores it, a deficiency can build slowly over months or years, which is why the early signs are easy to miss.

The symptoms to look for

The NHS lists tiredness, breathlessness, a pale or yellow tinge to the skin, a sore red tongue, mouth ulcers, pins and needles, muscle weakness, disturbed vision and changes in mood, memory or concentration. These overlap with many other conditions, so a test matters rather than guessing.

Who is most at risk

Deficiency is more common with age — the NHS notes it affects a higher proportion of people over 65. It is also more likely if you follow a vegan or vegetarian diet, since B12 comes mainly from meat, fish, eggs and dairy; if you have pernicious anaemia, an autoimmune condition affecting absorption; or if you take certain long-term medicines such as some for acid reflux or type 2 diabetes.

How it is diagnosed

A simple blood test measures your B12 level. It is worth testing before starting supplements, because supplementing first can mask the result. At South London Clinic, South London, we can arrange the test and discuss the result with you.

How it is treated

Treatment depends on the cause. Where it is dietary, high-dose tablets may be enough; where absorption is the problem, B12 injections are the usual route because they bypass the gut. Left untreated, deficiency can cause longer-term nerve problems, so it is worth acting on.

Common questions

Written and reviewed by

Reviewed by Rafay

Rafay Aslam

Rafay Aslam

Superintendent Pharmacist & Independent Prescriber

Rafay has been a pharmacist for more than 12 years and leads the clinical services at Hills Pharmacy. Articles here are written and checked against current NHS and UK guidance, and are general information — not a substitute for a consultation about your own health.

GPhC registration 2240995

Hills Pharmacy, 99 Kennington Lane, Kennington, South London SE11 4HQ — GPhC premises 1093041 (Marlborough UK Limited)

Reviewed by Rafay Aslam · 21 September 2026

Check on the GPhC register

Common questions

Can I just take B12 supplements without testing?

It is better to test first. Supplementing beforehand can mask a deficiency and hide its underlying cause, which may need different treatment.

Why injections rather than tablets?

If the problem is absorption — as in pernicious anaemia — injections bypass the gut and are more reliable. Where the cause is dietary, tablets may be enough. The pharmacist advises based on your situation.

How quickly will I feel better?

Many people notice more energy within a few weeks of starting treatment, though nerve-related symptoms can take longer to improve.

Is B12 deficiency serious?

Untreated, it can lead to lasting nerve damage and other complications, so it is worth diagnosing and treating rather than ignoring.

Ready to talk it through?

Book an appointment and a pharmacist will go through your situation with you and set out what's clinically appropriate — in plain language, with no pressure.

This article is general information and does not replace a consultation. Some treatments are prescription only medicines, supplied only after a clinical assessment.

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Appointments are with a pharmacist at Hills Pharmacy, 99 Kennington Lane — free parking nearby.

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South London Clinic at Hills Pharmacy, 99 Kennington Lane, Kennington, South London, Lambeth, SE11 4HQ · Free parking nearby

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Bookings for this clinic are taken by phone and email. Give us a call during opening hours and we'll go through the times that are free.

Opening hours

Monday – Friday
9:00 – 17:30
Saturday
9:00 – 13:00
Sunday
Closed

Appointments are subject to availability. If you are travelling, call as early as you can — some travel vaccines need a course started in advance.

Where to find us

Find us in South London

The clinic is inside Hills Pharmacy on High Street. Come in through the shop and tell the counter you're here for an appointment.

Address

South London Travel Clinic at Hills Pharmacy99 Kennington Lane
Kennington, South London
Lambeth SE11 4HQ

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Opening hours

Monday – Friday
9:00 – 17:30
Saturday
9:00 – 13:00
Sunday
Closed

Clinic appointments run within these hours. Bank holiday hours can differ — please call before travelling in.

South London Travel Clinic at Hills Pharmacy, 99 Kennington Lane, Kennington, Lambeth, SE11 4HQ

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